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Speckle-type POZ protein could play a potential inhibitory role in human renal cell carcinoma

BACKGROUND: Speckle-type POZ protein(SPOP), a substrate adaptor of Cul3 ubiquitin ligase, plays crucial roles in solid neoplasms by promoting the ubiquitination and degradation of substrates. Limited studies have shown that SPOP is overexpressed in human renal cell carcinoma (RCC) tissue. However, t...

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Detalles Bibliográficos
Autores principales: Chen, Zhi, Li, Zuan, Li, Chunlin, Li, Bingcai, Wang, Haojian, Nong, Deyong, Li, Ximing, Huang, Guihai, Lin, Junhao, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727862/
https://www.ncbi.nlm.nih.gov/pubmed/36474188
http://dx.doi.org/10.1186/s12885-022-10340-w