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MNX1-AS1, a c-Myc induced lncRNA, promotes the Warburg effect by regulating PKM2 nuclear translocation

BACKGROUND: Altered glycolysis is the most fundamental metabolic change associated with the Warburg effect. Some glycolytic enzymes such as PKM2, the dominant pyruvate kinase in cancer cells, have been shown to engage in non-glycolytic functions that contribute to tumor metabolism. However, the prec...

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Detalles Bibliográficos
Autores principales: Wu, Yang, Wang, Yichun, Yao, Hanhui, Li, Heng, Meng, Fanzheng, Li, Qidong, Lin, Xiansheng, Liu, Lianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727912/
https://www.ncbi.nlm.nih.gov/pubmed/36476366
http://dx.doi.org/10.1186/s13046-022-02547-3