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MNX1-AS1, a c-Myc induced lncRNA, promotes the Warburg effect by regulating PKM2 nuclear translocation
BACKGROUND: Altered glycolysis is the most fundamental metabolic change associated with the Warburg effect. Some glycolytic enzymes such as PKM2, the dominant pyruvate kinase in cancer cells, have been shown to engage in non-glycolytic functions that contribute to tumor metabolism. However, the prec...
Autores principales: | Wu, Yang, Wang, Yichun, Yao, Hanhui, Li, Heng, Meng, Fanzheng, Li, Qidong, Lin, Xiansheng, Liu, Lianxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727912/ https://www.ncbi.nlm.nih.gov/pubmed/36476366 http://dx.doi.org/10.1186/s13046-022-02547-3 |
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