PDK1- and PDK2-mediated metabolic reprogramming contributes to the TGFβ1-promoted stem-like properties in head and neck cancer

BACKGROUND: Resistance to chemotherapeutic drugs is a key factor for cancer recurrence and metastases in head and neck cancer (HNC). Cancer stem cells (CSCs) in tumors have self-renewal, differentiation, and higher drug resistance capabilities, resulting in a poor prognosis for patients. In glucose...

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Detalles Bibliográficos
Autores principales: Sun, Wan-Hsuan, Chen, Yun-Hsuan, Lee, Hou-Hsuan, Tang, Yu-Wen, Sun, Kuang-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727917/
https://www.ncbi.nlm.nih.gov/pubmed/36474273
http://dx.doi.org/10.1186/s40170-022-00300-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727917/
https://www.ncbi.nlm.nih.gov/pubmed/36474273
http://dx.doi.org/10.1186/s40170-022-00300-0

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