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Blocking STAT3/5 through direct or upstream kinase targeting in leukemic cutaneous T‐cell lymphoma

Leukemic cutaneous T‐cell lymphomas (L‐CTCL) are lymphoproliferative disorders of skin‐homing mature T‐cells causing severe symptoms and high mortality through chronic inflammation, tissue destruction, and serious infections. Despite numerous genomic sequencing efforts, recurrent driver mutations ha...

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Detalles Bibliográficos
Autores principales: Sorger, Helena, Dey, Saptaswa, Vieyra‐Garcia, Pablo Augusto, Pölöske, Daniel, Teufelberger, Andrea R, de Araujo, Elvin D, Sedighi, Abootaleb, Graf, Ricarda, Spiegl, Benjamin, Lazzeri, Isaac, Braun, Till, Garces de los Fayos Alonso, Ines, Schlederer, Michaela, Timelthaler, Gerald, Kodajova, Petra, Pirker, Christine, Surbek, Marta, Machtinger, Michael, Graier, Thomas, Perchthaler, Isabella, Pan, Yi, Fink‐Puches, Regina, Cerroni, Lorenzo, Ober, Jennifer, Otte, Moritz, Albrecht, Jana D, Tin, Gary, Abdeldayem, Ayah, Manaswiyoungkul, Pimyupa, Olaoye, Olasunkanmi O, Metzelder, Martin L, Orlova, Anna, Berger, Walter, Wobser, Marion, Nicolay, Jan P, André, Fiona, Nguyen, Van Anh, Neubauer, Heidi A, Fleck, Roman, Merkel, Olaf, Herling, Marco, Heitzer, Ellen, Gunning, Patrick T, Kenner, Lukas, Moriggl, Richard, Wolf, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727928/
https://www.ncbi.nlm.nih.gov/pubmed/36341492
http://dx.doi.org/10.15252/emmm.202115200