In vivo single‐cell transcriptomics reveal Klebsiella pneumoniae skews lung macrophages to promote infection

The strategies deployed by antibiotic‐resistant bacteria to counteract host defences are poorly understood. Here, we elucidate a novel host–pathogen interaction resulting in skewing lung macrophage polarisation by the human pathogen Klebsiella pneumoniae. We identify interstitial macrophages (IMs) a...

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Detalles Bibliográficos
Autores principales: Dumigan, Amy, Cappa, Oisin, Morris, Brenda, Sá Pessoa, Joana, Calderon‐Gonzalez, Ricardo, Mills, Grant, Lancaster, Rebecca, Simpson, David, Kissenpfennig, Adrien, Bengoechea, Jose A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727930/
https://www.ncbi.nlm.nih.gov/pubmed/36337046
http://dx.doi.org/10.15252/emmm.202216888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727930/
https://www.ncbi.nlm.nih.gov/pubmed/36337046
http://dx.doi.org/10.15252/emmm.202216888

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