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Synthesis and structural characterization of a new dinuclear platinum(III) complex, [Pt(2)Cl(4)(NH(3))(2){μ-HN=C(O)Bu(t)}(2)]
Cisplatin plays an important role in treating many tumors. However, its pharmacological potential is limited by several side effects (nephrotoxicity, neurotoxicity, hair loss) and the resistance of many cancer types. In the effort of overcome resistance to cisplatin, more than 3000 platinum complexe...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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International Union of Crystallography
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728019/ http://dx.doi.org/10.1107/S2052520622009660 |