Lactate dehydrogenases promote glioblastoma growth and invasion via a metabolic symbiosis

Lactate is a central metabolite in brain physiology but also contributes to tumor development. Glioblastoma (GB) is the most common and malignant primary brain tumor in adults, recognized by angiogenic and invasive growth, in addition to its altered metabolism. We show herein that lactate fuels GB a...

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Detalles Bibliográficos
Autores principales: Guyon, Joris, Fernandez‐Moncada, Ignacio, Larrieu, Claire M, Bouchez, Cyrielle L, Pagano Zottola, Antonio C, Galvis, Johanna, Chouleur, Tiffanie, Burban, Audrey, Joseph, Kevin, Ravi, Vidhya M, Espedal, Heidi, Røsland, Gro Vatne, Daher, Boutaina, Barre, Aurélien, Dartigues, Benjamin, Karkar, Slim, Rudewicz, Justine, Romero‐Garmendia, Irati, Klink, Barbara, Grützmann, Konrad, Derieppe, Marie‐Alix, Molinié, Thibaut, Obad, Nina, Léon, Céline, Seano, Giorgio, Miletic, Hrvoje, Heiland, Dieter Henrik, Marsicano, Giovanni, Nikolski, Macha, Bjerkvig, Rolf, Bikfalvi, Andreas, Daubon, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728051/
https://www.ncbi.nlm.nih.gov/pubmed/36278433
http://dx.doi.org/10.15252/emmm.202115343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728051/
https://www.ncbi.nlm.nih.gov/pubmed/36278433
http://dx.doi.org/10.15252/emmm.202115343

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