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Adoptive T cell therapy cures mice from active hemophagocytic lymphohistiocytosis (HLH)

Primary hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory syndrome caused by impaired lymphocyte cytotoxicity. First‐line therapeutic regimens directed against activated immune cells or secreted cytokines show limited efficacy since they do not target the underlying immunological probl...

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Detalles Bibliográficos
Autores principales: Weißert, Kristoffer, Ammann, Sandra, Kögl, Tamara, Dettmer‐Monaco, Viviane, Schell, Christoph, Cathomen, Toni, Ehl, Stephan, Aichele, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728053/
https://www.ncbi.nlm.nih.gov/pubmed/36278424
http://dx.doi.org/10.15252/emmm.202216085