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The AhR‐SRC axis as a therapeutic vulnerability in BRAFi‐resistant melanoma

The nongenetic mechanisms required to control tumor phenotypic plasticity and shape drug‐resistance remain unclear. We show here that the Aryl hydrocarbon Receptor (AhR) transcription factor directly regulates the gene expression program associated with the acquisition of resistance to BRAF inhibito...

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Detalles Bibliográficos
Autores principales: Paris, Anaïs, Tardif, Nina, Baietti, Francesca M, Berra, Cyrille, Leclair, Héloïse M, Leucci, Eleonora, Galibert, Marie‐Dominique, Corre, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728058/
https://www.ncbi.nlm.nih.gov/pubmed/36305167
http://dx.doi.org/10.15252/emmm.202215677