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The AhR‐SRC axis as a therapeutic vulnerability in BRAFi‐resistant melanoma
The nongenetic mechanisms required to control tumor phenotypic plasticity and shape drug‐resistance remain unclear. We show here that the Aryl hydrocarbon Receptor (AhR) transcription factor directly regulates the gene expression program associated with the acquisition of resistance to BRAF inhibito...
Autores principales: | Paris, Anaïs, Tardif, Nina, Baietti, Francesca M, Berra, Cyrille, Leclair, Héloïse M, Leucci, Eleonora, Galibert, Marie‐Dominique, Corre, Sébastien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728058/ https://www.ncbi.nlm.nih.gov/pubmed/36305167 http://dx.doi.org/10.15252/emmm.202215677 |
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