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Analogs of Periplanetasin-4 Exhibit Deteriorated Membrane-Targeted Action
Periplanetasin-4 is an antimicrobial peptide with 13 amino acids identified in cockroaches. It has been reported to induce fungal cell death by apoptosis and membrane-targeted action. Analogs were designed by substituting arginine residues to modify the electrostatic and hydrophobic interactions acc...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Korean Society for Microbiology and Biotechnology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728181/ https://www.ncbi.nlm.nih.gov/pubmed/32238758 http://dx.doi.org/10.4014/jmb.1912.12044 |