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Mec1 Modulates Interhomolog Crossover and Interplays with Tel1 at Post Double-Strand Break Stages

During meiosis I, programmed DNA double-strand breaks (DSBs) occur to promote chromosome pairing and recombination between homologs. In Saccharomyces cerevisiae, Mec1 and Tel1, the orthologs of human ATR and ATM, respectively, regulate events upstream of the cell cycle checkpoint to initiate DNA rep...

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Detalles Bibliográficos
Autores principales: Lee, Min-Su, Joo, Jung Whan, Choi, Hyungseok, Kang, Hyun Ah, Kim, Keunpil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Microbiology and Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728206/
https://www.ncbi.nlm.nih.gov/pubmed/31847509
http://dx.doi.org/10.4014/jmb.1909.09020