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Fluorometric Detection of Low-Abundance EGFR Exon 19 Deletion Mutation Using Tandem Gene Amplification

Epidermal growth factor receptor (EGFR) mutations are not only genetic markers for diagnosis but also biomarkers of clinical-response against tyrosine kinase inhibitors (TKIs) in non-small cell lung cancer (NSCLC). Among the EGFR mutations, the in-frame deletion mutation in EGFR exon 19 kinase domai...

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Detalles Bibliográficos
Autores principales: Kim, Dong-Min, Zhang, Shichen, Kim, Minhee, Kim, Dong-Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Microbiology and Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728277/
https://www.ncbi.nlm.nih.gov/pubmed/32482931
http://dx.doi.org/10.4014/jmb.2004.04010