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The Inhibition of MicroRNA-139-5p Promoted Osteoporosis of Bone Marrow-Derived Mesenchymal Stem Cells by Targeting Wnt/Beta- Catenin Signaling Pathway by NOTCH1

We investigated the therapeutic effects of microRNA-139-5p in relation to osteoporosis of bone marrow-derived mesenchymal stem cell (BMSCs) and its underlying mechanisms. In this study we used a dexamethasone-induced in vivo model of osteoporosis and BMSCs were used for the in vitro model. Real-time...

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Detalles Bibliográficos
Autores principales: Feng, Yimiao, Wan, Pengbo, Yin, Linling, Lou, Xintian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Microbiology and Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728286/
https://www.ncbi.nlm.nih.gov/pubmed/31752063
http://dx.doi.org/10.4014/jmb.1908.08036