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Characterization of CYP125A13, the First Steroid C-27 Monooxygenase from Streptomyces peucetius ATCC27952

The characterization of cytochrome P450 CYP125A13 from Streptomyces peucetius was conducted using cholesterol as the sole substrate. The in vitro enzymatic assay utilizing putidaredoxin and putidaredoxin reductase from Pseudomonas putida revealed that CYP125A13 bound cholesterol and hydroxylated it....

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Detalles Bibliográficos
Autores principales: Rimal, Hemraj, Subedi, Pradeep, Kim, Ki -Hwa, Park, Hyun, Lee, Jun Hyuck, Oh, Tae-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Microbiology and Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728343/
https://www.ncbi.nlm.nih.gov/pubmed/32958729
http://dx.doi.org/10.4014/jmb.2007.07004