CRM646-A, a Fungal Metabolite, Induces Nucleus Condensation by Increasing Ca(2+) Levels in Rat 3Y1 Fibroblast Cells

We previously identified a new heparinase inhibitor fungal metabolite, named CRM646-A, which showed inhibition of heparinase and telomerase activities in an in vitro enzyme assay and antimetastatic activity in a cell-based assay. In this study, we elucidated the mechanism by which CRM646-A rapidly i...

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Detalles Bibliográficos
Autores principales: Asami, Yukihiro, Kim, Sun-Ok, Jang, Jun-Pil, Ko, Sung-Kyun, Kim, Bo Yeon, Osada, Hiroyuki, Jang, Jae-Hyuk, Ahn, Jong Seog
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Microbiology and Biotechnology 2020
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728397/
https://www.ncbi.nlm.nih.gov/pubmed/31752054
http://dx.doi.org/10.4014/jmb.1908.08043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728397/
https://www.ncbi.nlm.nih.gov/pubmed/31752054
http://dx.doi.org/10.4014/jmb.1908.08043

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