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CRM646-A, a Fungal Metabolite, Induces Nucleus Condensation by Increasing Ca(2+) Levels in Rat 3Y1 Fibroblast Cells
We previously identified a new heparinase inhibitor fungal metabolite, named CRM646-A, which showed inhibition of heparinase and telomerase activities in an in vitro enzyme assay and antimetastatic activity in a cell-based assay. In this study, we elucidated the mechanism by which CRM646-A rapidly i...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Korean Society for Microbiology and Biotechnology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728397/ https://www.ncbi.nlm.nih.gov/pubmed/31752054 http://dx.doi.org/10.4014/jmb.1908.08043 |