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Laminin α1 as a target for the treatment of epidural fibrosis by regulating fibrotic mechanisms

Excessive proliferation and migration of fibroblasts in the lumbar laminectomy area can lead to epidural fibrosis, eventually resulting in failed back surgery syndrome. It has been reported that laminin α1, a significant biofunctional glycoprotein in the extracellular matrix, is involved in several...

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Detalles Bibliográficos
Autores principales: Liu, Pengran, Zhang, Dan, Huang, Guixiong, Xue, Mingdi, Fang, Ying, Lu, Lin, Zhang, Jiayao, Xie, Mao, Ye, Zhewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728507/
https://www.ncbi.nlm.nih.gov/pubmed/36382649
http://dx.doi.org/10.3892/ijmm.2022.5205