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AD‐associated CSF biomolecular changes are attenuated in KL‐VS heterozygotes

INTRODUCTION: Dementia as an inevitable aging consequence has been challenged and underscores the need for investigations of the factors that confer resilience. We examine whether the functionally advantageous KL‐VS variant of the putative aging suppressor KLOTHO gene attenuates age‐related cognitiv...

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Detalles Bibliográficos
Autores principales: Driscoll, Ira, Ma, Yue, Lose, Sarah R., Gallagher, Catherine L., Johnson, Sterling C., Asthana, Sanjay, Hermann, Bruce P., Sager, Mark A., Blennow, Kaj, Zetterberg, Henrik, Carlsson, Cynthia M., Engelman, Corinne D., Dubal, Dena B., Okonkwo, Ozioma C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728548/
https://www.ncbi.nlm.nih.gov/pubmed/36505396
http://dx.doi.org/10.1002/dad2.12383