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Adaptation in Outbred Sexual Yeast is Repeatable, Polygenic and Favors Rare Haplotypes

We carried out a 200 generation Evolve and Resequence (E&R) experiment initiated from an outbred diploid recombined 18-way synthetic base population. Replicate populations were evolved at large effective population sizes (>10(5) individuals), exposed to several different chemical challenges o...

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Detalles Bibliográficos
Autores principales: Linder, Robert A, Zabanavar, Behzad, Majumder, Arundhati, Hoang, Hannah Chiao-Shyan, Delgado, Vanessa Genesaret, Tran, Ryan, La, Vy Thoai, Leemans, Simon William, Long, Anthony D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728589/
https://www.ncbi.nlm.nih.gov/pubmed/36366952
http://dx.doi.org/10.1093/molbev/msac248