Doxycycline attenuates l-DOPA-induced dyskinesia through an anti-inflammatory effect in a hemiparkinsonian mouse model

The pharmacological manipulation of neuroinflammation appears to be a promising strategy to alleviate l-DOPA-induced dyskinesia (LID) in Parkinson’s disease (PD). Doxycycline (Doxy), a semisynthetic brain-penetrant tetracycline antibiotic having interesting anti-inflammatory properties, we addressed...

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Detalles Bibliográficos
Autores principales: dos Santos Pereira, Maurício, do Nascimento, Glauce Crivelaro, Bortolanza, Mariza, Michel, Patrick Pierre, Raisman-Vozari, Rita, Del Bel, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728610/
https://www.ncbi.nlm.nih.gov/pubmed/36506543
http://dx.doi.org/10.3389/fphar.2022.1045465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728610/
https://www.ncbi.nlm.nih.gov/pubmed/36506543
http://dx.doi.org/10.3389/fphar.2022.1045465

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