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MicroRNA-181a regulates Treg functions via TGF-β1/Smad axis in the spleen of mice with acute gouty arthritis induced by MSU crystals

Regulatory T cells (Tregs) play critical roles in restricting inflammatory pathogenesis and limiting undesirable Th2 response to environmental allergens. However, the role of miR-181a in regulating acute gouty arthritis (AGA) and Treg function remains unclear. This study aimed to investigate the pot...

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Detalles Bibliográficos
Autores principales: Wang, Yu, Tu, Shenghao, Huang, Ying, Qin, Kai, Chen, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728631/
https://www.ncbi.nlm.nih.gov/pubmed/36477951
http://dx.doi.org/10.1590/1414-431X2022e12002