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Analysis of cataract-regulated genes using chemical DNA damage induction in a rat ex vivo model

Although cataracts affect almost all people at advanced age and carry a risk of blindness, the mechanisms of cataract development remain incompletely understood. Oxidative stress, which is a causative factor in cataract, results in DNA breakage, which suggests that DNA damage could contribute to the...

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Detalles Bibliográficos
Autores principales: Yamaoka, Risa, Kanada, Fumito, Nagaya, Masaya, Takashima, Masaru, Takamura, Yoshihiro, Inatani, Masaru, Oki, Masaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728860/
https://www.ncbi.nlm.nih.gov/pubmed/36477544
http://dx.doi.org/10.1371/journal.pone.0273456