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Immunomodulatory drug fingolimod (FTY720) restricts the growth of opportunistic yeast Candida albicans in vitro and in a mouse candidiasis model

Fingolimod (FTY720) is a drug derived from the fungicidal compound myriocin. As it was unclear whether FTY720 has antifungal effects as well, we aimed to characterize its effect on Candida albicans in vitro and in a mouse candidiasis model. First, antifungal susceptibility testing was performed in v...

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Detalles Bibliográficos
Autores principales: Najarzadegan, Niloofar, Madani, Mahboobeh, Etemadifar, Masoud, Sedaghat, Nahad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728862/
https://www.ncbi.nlm.nih.gov/pubmed/36477491
http://dx.doi.org/10.1371/journal.pone.0278488