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The Salmonella T3SS1 effector IpaJ is regulated by ItrA and inhibits the MAPK signaling pathway

Invasion plasmid antigen J (IpaJ) is a protein with cysteine protease activity that is present in Salmonella and Shigella species. Salmonella enterica serovar Pullorum uses IpaJ to inhibit the NF-κB pathway and the subsequent inflammatory response, resulting in bacterial survival in host macrophages...

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Detalles Bibliográficos
Autores principales: Yin, Chao, Gu, Jiaojie, Gu, Dan, Wang, Zhenyu, Ji, Ruoyun, Jiao, Xinan, Li, Qiuchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728880/
https://www.ncbi.nlm.nih.gov/pubmed/36477497
http://dx.doi.org/10.1371/journal.ppat.1011005