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Genetic risk scores and dementia risk across different ethnic groups in UK Biobank

BACKGROUND: Genetic Risk Scores (GRS) for predicting dementia risk have mostly been used in people of European ancestry with limited testing in other ancestry groups. METHODS: We conducted a logistic regression with all-cause dementia as the outcome and z-standardised GRS as the exposure across dive...

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Detalles Bibliográficos
Autores principales: Mukadam, Naaheed, Giannakopoulou, Olga, Bass, Nick, Kuchenbaecker, Karoline, McQuillin, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728885/
https://www.ncbi.nlm.nih.gov/pubmed/36477264
http://dx.doi.org/10.1371/journal.pone.0277378