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GW-2974 and SCH-442416 modulators of tyrosine kinase and adenosine receptors can also stabilize human telomeric G-quadruplex DNA

GW-2974 is a potent tyrosine kinase receptor inhibitor while SCH-442416 is a potent adenosine receptors’ antagonist with high selectivity towards human adenosine A(2A) receptor over other adenosine receptors. The two compounds were reported to possess anti-cancer properties. This study aimed to inve...

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Detalles Bibliográficos
Autores principales: Salem, Alaa A., El Haty, Ismail A., Ghattas, Mohammad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728906/
https://www.ncbi.nlm.nih.gov/pubmed/36476719
http://dx.doi.org/10.1371/journal.pone.0277963