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Comparing T cell receptor repertoires using optimal transport

The complexity of entire T cell receptor (TCR) repertoires makes their comparison a difficult but important task. Current methods of TCR repertoire comparison can incur a high loss of distributional information by considering overly simplistic sequence- or repertoire-level characteristics. Optimal t...

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Detalles Bibliográficos
Autores principales: Olson, Branden J., Schattgen, Stefan A., Thomas, Paul G., Bradley, Philip, Matsen IV, Frederick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728925/
https://www.ncbi.nlm.nih.gov/pubmed/36476997
http://dx.doi.org/10.1371/journal.pcbi.1010681