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A myocardial infarct border-zone-on-a-chip demonstrates distinct regulation of cardiac tissue function by an oxygen gradient

After a myocardial infarction, the boundary between the injured, hypoxic tissue and the adjacent viable, normoxic tissue, known as the border zone, is characterized by an oxygen gradient. Yet, the impact of an oxygen gradient on cardiac tissue function is poorly understood, largely due to limitation...

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Detalles Bibliográficos
Autores principales: Rexius-Hall, Megan L., Khalil, Natalie N., Escopete, Sean S., Li, Xin, Hu, Jiayi, Yuan, Hongyan, Parker, Sarah J., McCain, Megan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728975/
https://www.ncbi.nlm.nih.gov/pubmed/36475790
http://dx.doi.org/10.1126/sciadv.abn7097