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A myocardial infarct border-zone-on-a-chip demonstrates distinct regulation of cardiac tissue function by an oxygen gradient
After a myocardial infarction, the boundary between the injured, hypoxic tissue and the adjacent viable, normoxic tissue, known as the border zone, is characterized by an oxygen gradient. Yet, the impact of an oxygen gradient on cardiac tissue function is poorly understood, largely due to limitation...
Autores principales: | Rexius-Hall, Megan L., Khalil, Natalie N., Escopete, Sean S., Li, Xin, Hu, Jiayi, Yuan, Hongyan, Parker, Sarah J., McCain, Megan L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728975/ https://www.ncbi.nlm.nih.gov/pubmed/36475790 http://dx.doi.org/10.1126/sciadv.abn7097 |
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