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Physical Characteristics of von Willebrand Factor Binding with Platelet Glycoprotein Ibɑ Mutants at Residue 233 Causing Various Biological Functions

Glycoprotein (GP: HIS (1) -PRO (265) ) Ibɑ is a receptor protein expressed on the surface of the platelet. Its N-terminus domain binds with the A1 domain (ASP (1269) -PRO (1472) ) of its ligand protein von Willebrand factor (VWF) and plays a unique role in platelet adhesion under blood flow conditio...

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Detalles Bibliográficos
Autores principales: Nakayama, Masamitsu, Goto, Shinichi, Goto, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729063/
https://www.ncbi.nlm.nih.gov/pubmed/36632284
http://dx.doi.org/10.1055/a-1937-9940