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Gradual differentiation uncoupled from cell cycle exit generates heterogeneity in the epidermal stem cell layer
Highly regenerative tissues continuously produce terminally differentiated cells to replace those that are lost. How they orchestrate the complex transition from undifferentiated stem cells towards post-mitotic, molecularly distinct and often spatially segregated differentiated populations is not we...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729105/ https://www.ncbi.nlm.nih.gov/pubmed/36357619 http://dx.doi.org/10.1038/s41556-022-01021-8 |