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ER-associated RNA silencing promotes ER quality control

The endoplasmic reticulum (ER) coordinates mRNA translation and processing of secreted and endomembrane proteins. ER-associated degradation (ERAD) prevents the accumulation of misfolded proteins in the ER, but the physiological regulation of this process remains poorly characterized. Here, in a gene...

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Detalles Bibliográficos
Autores principales: Efstathiou, Sotirios, Ottens, Franziska, Schütter, Lena-Sophie, Ravanelli, Sonia, Charmpilas, Nikolaos, Gutschmidt, Aljona, Le Pen, Jérémie, Gehring, Niels H., Miska, Eric A., Bouças, Jorge, Hoppe, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729107/
https://www.ncbi.nlm.nih.gov/pubmed/36471127
http://dx.doi.org/10.1038/s41556-022-01025-4