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The effects of microglia on tauopathy progression can be quantified using Nexopathy in silico (Nexis) models

The prion-like transsynaptic propagation of misfolded tau along the brain’s connectome has previously been modeled using connectome-based network diffusion models. In addition to the connectome, interactions between the general neurological “milieu” in the neurodegenerative brain and proteinopathic...

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Detalles Bibliográficos
Autores principales: Anand, Chaitali, Maia, Pedro D., Torok, Justin, Mezias, Christopher, Raj, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729195/
https://www.ncbi.nlm.nih.gov/pubmed/36477076
http://dx.doi.org/10.1038/s41598-022-25131-3