Dissecting aggregation and seeding dynamics of α-Syn polymorphs using the phasor approach to FLIM

Synucleinopathies are a heterogenous group of neurodegenerative diseases characterized by the progressive accumulation of pathological α-synuclein (α-Syn). The importance of structural polymorphism of α-Syn assemblies for distinct synucleinopathies and their progression is increasingly recognized. H...

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Detalles Bibliográficos
Autores principales: Tittelmeier, Jessica, Druffel-Augustin, Silke, Alik, Ania, Melki, Ronald, Nussbaum-Krammer, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729209/
https://www.ncbi.nlm.nih.gov/pubmed/36477485
http://dx.doi.org/10.1038/s42003-022-04289-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729209/
https://www.ncbi.nlm.nih.gov/pubmed/36477485
http://dx.doi.org/10.1038/s42003-022-04289-6

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