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Dissecting aggregation and seeding dynamics of α-Syn polymorphs using the phasor approach to FLIM
Synucleinopathies are a heterogenous group of neurodegenerative diseases characterized by the progressive accumulation of pathological α-synuclein (α-Syn). The importance of structural polymorphism of α-Syn assemblies for distinct synucleinopathies and their progression is increasingly recognized. H...
Autores principales: | Tittelmeier, Jessica, Druffel-Augustin, Silke, Alik, Ania, Melki, Ronald, Nussbaum-Krammer, Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729209/ https://www.ncbi.nlm.nih.gov/pubmed/36477485 http://dx.doi.org/10.1038/s42003-022-04289-6 |
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