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Lipid desaturation regulates the balance between self-renewal and differentiation in mouse blastocyst-derived stem cells

Stem cells are defined by their ability to self-renew and differentiate, both shown in multiple studies to be regulated by metabolic processes. To decipher metabolic signatures of self-renewal in blastocyst-derived stem cells, we compared early differentiating embryonic stem cells (ESCs) and their e...

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Detalles Bibliográficos
Autores principales: Mannully, Chanchal Thomas, Bruck-Haimson, Reut, Zacharia, Anish, Orih, Paul, Shehadeh, Alaa, Saidemberg, Daniel, Kogan, Natalya M., Alfandary, Sivan, Serruya, Raphael, Dagan, Arie, Petit, Isabelle, Moussaieff, Arieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729213/
https://www.ncbi.nlm.nih.gov/pubmed/36477438
http://dx.doi.org/10.1038/s41419-022-05263-0