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The mitochondrial Ca(2+) uniporter channel synergizes with fluid shear stress to induce mitochondrial Ca(2+) oscillations

The mitochondrial calcium (Ca(2+)) uniporter (MCU) channel is responsible for mitochondrial Ca(2+) influx. Its expression was found to be upregulated in endothelial cells (ECs) under cardiovascular disease conditions. Since the role of MCU in regulating cytosolic Ca(2+) homeostasis in ECs exposed to...

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Detalles Bibliográficos
Autores principales: Patel, Akshar, Simkulet, Matthew, Maity, Soumya, Venkatesan, Manigandan, Matzavinos, Anastasios, Madesh, Muniswamy, Alevriadou, B. Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729216/
https://www.ncbi.nlm.nih.gov/pubmed/36476944
http://dx.doi.org/10.1038/s41598-022-25583-7