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The mitochondrial Ca(2+) uniporter channel synergizes with fluid shear stress to induce mitochondrial Ca(2+) oscillations
The mitochondrial calcium (Ca(2+)) uniporter (MCU) channel is responsible for mitochondrial Ca(2+) influx. Its expression was found to be upregulated in endothelial cells (ECs) under cardiovascular disease conditions. Since the role of MCU in regulating cytosolic Ca(2+) homeostasis in ECs exposed to...
Autores principales: | Patel, Akshar, Simkulet, Matthew, Maity, Soumya, Venkatesan, Manigandan, Matzavinos, Anastasios, Madesh, Muniswamy, Alevriadou, B. Rita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729216/ https://www.ncbi.nlm.nih.gov/pubmed/36476944 http://dx.doi.org/10.1038/s41598-022-25583-7 |
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