Funnel metadynamics and behavioral studies reveal complex effect of D2AAK1 ligand on anxiety-like processes

Anxiety is a troublesome symptom for many patients, especially those suffering from schizophrenia. Its regulation involves serotonin receptors, targeted e.g. by antipsychotics or psychedelics such as LSD. 5-HT(2A) receptors are known for an extremely long LSD residence time, enabling minute doses to...

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Detalles Bibliográficos
Autores principales: Bartuzi, Damian, Kędzierska, Ewa, Targowska-Duda, Katarzyna M., Koszła, Oliwia, Wróbel, Tomasz M., Jademyr, Simon, Karcz, Tadeusz, Szczepańska, Katarzyna, Stępnicki, Piotr, Wronikowska-Denysiuk, Olga, Biała, Grażyna, Handzlik, Jadwiga, Kristensen, Jesper L., Poso, Antti, Kaczor, Agnieszka A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729218/
https://www.ncbi.nlm.nih.gov/pubmed/36476619
http://dx.doi.org/10.1038/s41598-022-25478-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729218/
https://www.ncbi.nlm.nih.gov/pubmed/36476619
http://dx.doi.org/10.1038/s41598-022-25478-7

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