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Membrane-mediated interaction of non-conventional snake three-finger toxins with nicotinic acetylcholine receptors

Nicotinic acetylcholine receptor of α7 type (α7-nAChR) presented in the nervous and immune systems and epithelium is a promising therapeutic target for cognitive disfunctions and cancer treatment. Weak toxin from Naja kaouthia venom (WTX) is a non-conventional three-finger neurotoxin, targeting α7-n...

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Detalles Bibliográficos
Autores principales: Shenkarev, Zakhar O., Chesnokov, Yuri M., Zaigraev, Maxim M., Chugunov, Anton O., Kulbatskii, Dmitrii S., Kocharovskaya, Milita V., Paramonov, Alexander S., Bychkov, Maxim L., Shulepko, Mikhail A., Nolde, Dmitry E., Kamyshinsky, Roman A., Yablokov, Evgeniy O., Ivanov, Alexey S., Kirpichnikov, Mikhail P., Lyukmanova, Ekaterina N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729238/
https://www.ncbi.nlm.nih.gov/pubmed/36477694
http://dx.doi.org/10.1038/s42003-022-04308-6