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Membrane-mediated interaction of non-conventional snake three-finger toxins with nicotinic acetylcholine receptors
Nicotinic acetylcholine receptor of α7 type (α7-nAChR) presented in the nervous and immune systems and epithelium is a promising therapeutic target for cognitive disfunctions and cancer treatment. Weak toxin from Naja kaouthia venom (WTX) is a non-conventional three-finger neurotoxin, targeting α7-n...
Autores principales: | Shenkarev, Zakhar O., Chesnokov, Yuri M., Zaigraev, Maxim M., Chugunov, Anton O., Kulbatskii, Dmitrii S., Kocharovskaya, Milita V., Paramonov, Alexander S., Bychkov, Maxim L., Shulepko, Mikhail A., Nolde, Dmitry E., Kamyshinsky, Roman A., Yablokov, Evgeniy O., Ivanov, Alexey S., Kirpichnikov, Mikhail P., Lyukmanova, Ekaterina N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729238/ https://www.ncbi.nlm.nih.gov/pubmed/36477694 http://dx.doi.org/10.1038/s42003-022-04308-6 |
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