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Multiregional single-cell dissection of tumor and immune cells reveals stable lock-and-key features in liver cancer

Intratumor heterogeneity may result from the evolution of tumor cells and their continuous interactions with the tumor microenvironment which collectively drives tumorigenesis. However, an appearance of cellular and molecular heterogeneity creates a challenge to define molecular features linked to t...

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Detalles Bibliográficos
Autores principales: Ma, Lichun, Heinrich, Sophia, Wang, Limin, Keggenhoff, Friederike L., Khatib, Subreen, Forgues, Marshonna, Kelly, Michael, Hewitt, Stephen M., Saif, Areeba, Hernandez, Jonathan M., Mabry, Donna, Kloeckner, Roman, Greten, Tim F., Chaisaingmongkol, Jittiporn, Ruchirawat, Mathuros, Marquardt, Jens U., Wang, Xin Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729309/
https://www.ncbi.nlm.nih.gov/pubmed/36476645
http://dx.doi.org/10.1038/s41467-022-35291-5