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Multiregional single-cell dissection of tumor and immune cells reveals stable lock-and-key features in liver cancer
Intratumor heterogeneity may result from the evolution of tumor cells and their continuous interactions with the tumor microenvironment which collectively drives tumorigenesis. However, an appearance of cellular and molecular heterogeneity creates a challenge to define molecular features linked to t...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729309/ https://www.ncbi.nlm.nih.gov/pubmed/36476645 http://dx.doi.org/10.1038/s41467-022-35291-5 |