Aporphine and isoquinoline derivatives block glioblastoma cell stemness and enhance temozolomide cytotoxicity

Glioblastoma (GBM) is the most aggressive and common primary malignant brain tumor with limited available therapeutic approaches. Despite improvements in therapeutic options for GBM patients, efforts to develop new successful strategies remain as major unmet medical needs. Based on the cytotoxic pro...

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Detalles Bibliográficos
Autores principales: Rodrigues-Junior, Dorival Mendes, Raminelli, Cristiano, Hassanie, Haifa, Trossini, Gustavo Henrique Goulart, Perecim, Givago Prado, Caja, Laia, Moustakas, Aristidis, Vettore, André Luiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729571/
https://www.ncbi.nlm.nih.gov/pubmed/36477472
http://dx.doi.org/10.1038/s41598-022-25534-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729571/
https://www.ncbi.nlm.nih.gov/pubmed/36477472
http://dx.doi.org/10.1038/s41598-022-25534-2

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