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Fabrication of a controlled-release delivery system for relieving sciatica nerve pain using an ultrasound-responsive microcapsule

Lidocaine, a potent local anesthetic, is clinically used in nerve block and pain management. However, due to its short half-life, repeated administration is required. For this reason, here we designed and prepared a lidocaine-encapsulated polylactic acid-glycolic acid (Lidocaine@PLGA) microcapsule w...

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Detalles Bibliográficos
Autores principales: Xu, Xiong, Chang, Shuai, Zhang, Xiaoyi, Hou, Taotao, Yao, Hui, Zhang, Shusheng, Zhu, Yuqi, Cui, Xu, Wang, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729723/
https://www.ncbi.nlm.nih.gov/pubmed/36507268
http://dx.doi.org/10.3389/fbioe.2022.1072205