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The transcriptomic landscape of elderly acute myeloid leukemia identifies B7H3 and BANP as a favorable signature in high-risk patients

Acute myeloid leukemia (AML) in the elderly remains a clinical challenge, with a five-year overall survival rate below 10%. The current ELN 2017 genetic risk classification considers cytogenetic and mutational characteristics to stratify fit AML patients into different prognostic groups. However, th...

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Detalles Bibliográficos
Autores principales: Villar, Sara, Ariceta, Beñat, Agirre, Xabier, Urribarri, Aura Daniela, Ayala, Rosa, Martínez-Cuadrón, David, Bergua, Juan Miguel, Vives, Susana, Algarra, Lorenzo, Tormo, Mar, Martínez, Pilar, Serrano, Josefina, Simoes, Catia, Herrera, Pilar, Calasanz, Maria José, Alfonso-Piérola, Ana, Paiva, Bruno, Martínez-López, Joaquín, San Miguel, Jesús F., Prósper, Felipe, Montesinos, Pau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729799/
https://www.ncbi.nlm.nih.gov/pubmed/36505804
http://dx.doi.org/10.3389/fonc.2022.1054458