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Sugar and spice: Fc glycosylation in antibody-mediated transplant rejection
Bharadwaj et al.(1) demonstrate that anti-donor HLA antibodies display low levels of Fc fucosylation. This signature was associated with potent provocation of NK cell effector functions and was discriminative for active antibody-mediated rejection among patients with donor specific HLA antibodies.
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729816/ https://www.ncbi.nlm.nih.gov/pubmed/36384088 http://dx.doi.org/10.1016/j.xcrm.2022.100809 |