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Sugar and spice: Fc glycosylation in antibody-mediated transplant rejection
Bharadwaj et al.(1) demonstrate that anti-donor HLA antibodies display low levels of Fc fucosylation. This signature was associated with potent provocation of NK cell effector functions and was discriminative for active antibody-mediated rejection among patients with donor specific HLA antibodies.
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729816/ https://www.ncbi.nlm.nih.gov/pubmed/36384088 http://dx.doi.org/10.1016/j.xcrm.2022.100809 |
| _version_ | 1784845552939171840 |
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| author | Valenzuela, Nicole M. |
| author_facet | Valenzuela, Nicole M. |
| author_sort | Valenzuela, Nicole M. |
| collection | PubMed |
| description | Bharadwaj et al.(1) demonstrate that anti-donor HLA antibodies display low levels of Fc fucosylation. This signature was associated with potent provocation of NK cell effector functions and was discriminative for active antibody-mediated rejection among patients with donor specific HLA antibodies. |
| format | Online Article Text |
| id | pubmed-9729816 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-97298162022-12-09 Sugar and spice: Fc glycosylation in antibody-mediated transplant rejection Valenzuela, Nicole M. Cell Rep Med Preview Bharadwaj et al.(1) demonstrate that anti-donor HLA antibodies display low levels of Fc fucosylation. This signature was associated with potent provocation of NK cell effector functions and was discriminative for active antibody-mediated rejection among patients with donor specific HLA antibodies. Elsevier 2022-11-15 /pmc/articles/PMC9729816/ /pubmed/36384088 http://dx.doi.org/10.1016/j.xcrm.2022.100809 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| spellingShingle | Preview Valenzuela, Nicole M. Sugar and spice: Fc glycosylation in antibody-mediated transplant rejection |
| title | Sugar and spice: Fc glycosylation in antibody-mediated transplant rejection |
| title_full | Sugar and spice: Fc glycosylation in antibody-mediated transplant rejection |
| title_fullStr | Sugar and spice: Fc glycosylation in antibody-mediated transplant rejection |
| title_full_unstemmed | Sugar and spice: Fc glycosylation in antibody-mediated transplant rejection |
| title_short | Sugar and spice: Fc glycosylation in antibody-mediated transplant rejection |
| title_sort | sugar and spice: fc glycosylation in antibody-mediated transplant rejection |
| topic | Preview |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729816/ https://www.ncbi.nlm.nih.gov/pubmed/36384088 http://dx.doi.org/10.1016/j.xcrm.2022.100809 |
| work_keys_str_mv | AT valenzuelanicolem sugarandspicefcglycosylationinantibodymediatedtransplantrejection |